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Journal / Cancer Research / Murine Pankreatik Duktal Adenokarsinomun Ultrason …
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Cancer Research

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JoVE Journal Cancer Research
Murine Pankreatik Duktal Adenokarsinomun Ultrason Eşliğinde Ortotopik İmplantasyonu
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Murine Pankreatik Duktal Adenokarsinomun Ultrason Eşliğinde Ortotopik İmplantasyonu

Article DOI: 10.3791/60497-v • 06:21 min • November 19th, 2019
November 19th, 2019 •
1, 2,3, 2,3, 2,3, 1,4
1Department of Medicine, Perelman School of Medicine, University of Pennsylvania, 2Pancreatic Cancer Mouse Hospital, Perelman School of Medicine, University of Pennsylvania, 3Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, 4Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania

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Biz doğrudan yerli tümör bölgesine mürin türetilmiş pankreas duktal adenokarsinom hücre hatlarının ultrason güdümlü implantasyonu için bir protokol açıklar. Bu yaklaşım, enjeksiyondan sonraki 2-4 hafta içinde ultrason taraması ile saptanabilen pankreas tümörlerinin saptanmasıyla sonuçlandı ve cerrahi ortotopik implantasyona kıyasla periton duvarındaki tümör hücre tohumlama oranını önemli ölçüde azalttı.

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Kanser Araştırma Sayı 153 pankreas duktal adenokarsinom ultrason ortotopik preklinik model
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