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JoVE Journal Medicine
Hæmorikompatibilitet test af blod-kontakt implantater i en Flow Loop Model efterligne humanblodgennemstrømning
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Hæmorikompatibilitet test af blod-kontakt implantater i en Flow Loop Model efterligne humanblodgennemstrømning

Article DOI: 10.3791/60610-v • 09:41 min • March 5th, 2020
March 5th, 2020 •
1, 2,3, 4, 4, 4, 1, 1, 1, 1
1Department of Thoracic, Cardiac and Vascular Surgery, University Hospital Tuebingen, 2Acandis GmbH, 3Institute of Biomedical Engineering, University of Stuttgart, 4Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic

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Denne protokol beskriver en omfattende hæmorikompatibilitet evaluering af blod-kontakt enheder ved hjælp af laser-cut neurovaskulære implantater. En flow loop model med frisk, heparinized humant blod anvendes til at efterligne blodgennemstrømningen. Efter perfusion analyseres forskellige hæmatologiske markører og sammenlignes med de værdier, der opnås umiddelbart efter blodtapning for hæmorikompatibilitetsevaluering af de testede enheder.

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Medicin hæmogomkompatibilitet flow loop model blod-kontaktenheder humant blod ISO 10993-4 evaluering af medicinsk udstyr
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