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Journal / Chemistry / 18 F-labeling van Radiotracers Functionaliseerde…
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JoVE Journal Chemistry
18 F-labeling van Radiotracers Functionaliseerde met een Siliciumfluoride acceptor (SiFA) voor positron emissie tomografie
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18 F-labeling van Radiotracers Functionaliseerde met een Siliciumfluoride acceptor (SiFA) voor positron emissie tomografie

Article DOI: 10.3791/60623-v • 09:57 min • January 11th, 2020
January 11th, 2020 •
*1, *1, 2,3, 2,3, 4, 5, 1, 1, 1
1Department of Oncology, University of Alberta, 2Department of Nuclear Medicine, University Hospital of Munich, 3ENETS Centre of Excellence, Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, LMU Munich, 4Biomedical Chemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University, 5Molecular Imaging and Radiochemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University
* These authors contributed equally

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De synthese van fluor-18 (18F) gelabelde radiofarmaceutica voor positron emissie tomografie vereist meestal maanden ervaring. Wanneer de siliconen-fluoride acceptor (SiFA) in een radio Tracer wordt verwerkt, is een eenvoudig 18F-labeling protocol mogelijk dat onafhankelijk is van kostbare apparatuur en voorbereidende training, terwijl de precursor hoeveelheid die nodig is en mildere reactie condities worden verminderd.

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Scheikunde uitgave 155 18F-radiolabeling radio Tracer in vivo beeldvorming positron emissie TOMOGRAFIE (PET) fluorine-18 silicium-fluoride acceptor (Sifa)
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