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Journal / Genetics / Exon Hoppe i direkte omprogrammerte myotubes…
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Genetics

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JoVE Journal Genetics
Exon Hoppe i direkte omprogrammerte myotubes hentet fra humane urin-avledede celler
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Exon Hoppe i direkte omprogrammerte myotubes hentet fra humane urin-avledede celler

Article DOI: 10.3791/60840-v • 06:20 min • May 7th, 2020
May 7th, 2020 •
1, 1, 1
1Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry

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I denne artikkelen beskriver vi en detaljert protokoll for effektiv modellering av Duchenne muskeldystrofi muskel ved hjelp av MYOD1-konverterturin-avledede celler for å evaluere restaureringen av dystrophin mRNA og proteinnivåer etter exon skipping.

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Genetikk Utgave 159 Duchenne muskeldystrofi (DMD) urinavledede celler exon hoppe presisjon medisin skjelettmuskulatur klinisk studie
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