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Journal / Genetics / Exon Springer i direkte omprogrammeret Myotubes…
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Genetics

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Exon Springer i direkte omprogrammeret Myotubes fremstillet af humane urin-afledte celler
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Exon Springer i direkte omprogrammeret Myotubes fremstillet af humane urin-afledte celler

Article DOI: 10.3791/60840-v • 06:20 min • May 7th, 2020
May 7th, 2020 •
1, 1, 1
1Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry

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I denne artikel beskriver vi en detaljeret protokol for effektiv modellering af Duchenne muskelsvind muskel ved hjælp af MYOD1-konverteredeurin-afledte celler til at evaluere restaureringen af dystrophin mRNA og protein niveauer efter exon springe.

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Genetik Duchenne muskelsvind (DMD) urin-afledte celler exon springe præcision medicin skeletmuskulatur klinisk forsøg
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