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JoVE Journal Bioengineering
Mikrofluidic Produktion af Lysolipid-Holdige Temperatur-Følsomme Liposomer
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Mikrofluidic Produktion af Lysolipid-Holdige Temperatur-Følsomme Liposomer

Article DOI: 10.3791/60907-v • 09:51 min • March 3rd, 2020
March 3rd, 2020 •
1, 1, 1, 1
1School of Pharmacy, Queen's University Belfast

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Protokollen præsenterer de optimerede parametre for forberedelse termofølsomme liposomer ved hjælp af forskudt sildeben micromixer microfluidics enhed. Dette giver også mulighed for co-indkapsling af doxorubicin og indocyanin grøn i liposomer og fototermisk-udløst frigivelse af doxorubicin for kontrolleret / udløst narkotika frigivelse.

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Bioengineering mikrofluidik liposomer termofølsomme lysolipid LCL'er forskudt sildeben micromixer kolesterol-fri indocyanin grøn (ICG) doxorubicin loading (DOX)
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