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A Rabbit Venous Interposition Model Mimicking Revascularization Surgery using Vein Grafts to Assess Intimal Hyperplasia under Arterial Blood Pressure

Article DOI: 10.3791/60931-v • 07:02 min • May 15th, 2020
May 15th, 2020 •
1,3, 1, 1,2
1Department of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University, 2Clinical Translational Research Program, RIKEN Center for Biosystems Dynamics Research, 3Department of Cardiovascular Surgery, Takamatsu Red Cross Hospital

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Summary
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The present protocol aims to experimentally create venous intimal hyperplasia by subjecting veins to arterial blood pressure for developing strategies to attenuate venous intimal hyperplasia following revascularization surgery using vein grafts.

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Rabbit Venous Interposition Model Revascularization Surgery Vein Grafts Intimal Hyperplasia Arterial Blood Pressure Protocol Researchers In Vitro Outcomes In Vivo Setting Animal Model Treatment Strategies Ischemic Heart Lower Extremity Diseases Cardiovascular Surgery Arteriovenous Fistulas End Stage Renal Disease Local Anesthetic Prophylactic Antibiotic Analgesic Administration Surgical Site Disinfection Incision Surgical Scalpel Cervical Region Japanese White Rabbit Subcutaneous Tissues Fascia Jugular Vein Segment Silk Sutures Balloon Catheter
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