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Montagem dirigida de proteínas semelhantes à elastina em estruturas supramoleculares definidas e encapsulamento de carga in vitro
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Montagem dirigida de proteínas semelhantes à elastina em estruturas supramoleculares definidas e encapsulamento de carga in vitro

Article DOI: 10.3791/60935-v • 10:01 min • April 8th, 2020
April 8th, 2020 •
*1,2, *1,2, 1,2, 1,2, 1,2,3,4,5,6
1Center for Biological Systems Analysis, University of Freiburg, 2Faculty of Biology, University of Freiburg, 3Freiburg Institute for Advanced Studies (FRIAS), University of Freiburg, 4BIOSS Centre for Biological Signalling Studies, University of Freiburg, 5IMTEK Department of Microsystems Engineering, University of Freiburg, 6Cluster of Excellence livMatS at FIT - Freiburg Center for Interactive Materials and Bioinspired Technologies, University of Freiburg
* These authors contributed equally

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Na interface de solventes orgânicos e aquosos, proteínas anfífilas sob medida se reúnem em estruturas supramoleculares complexas, como vesículas, fibras e coacervates desencadeadas por parâmetros ambientais. Os protocolos de montagem descritos produzem compartimentos baseados em membrana sérica (PMBCs) com propriedades ajustáveis, permitindo o encapsulamento de várias cargas.

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Química Edição 158 proteínas semelhantes à elastina vesículas à base de proteínas fibras proteicas sistemas de entrega de drogas auto-montagem membrana proteica
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