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JoVE Journal Chemistry
Riktad montering av Elastin-liknande proteiner i definierade supramolekylära strukturer och lastinkapsling In Vitro
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Riktad montering av Elastin-liknande proteiner i definierade supramolekylära strukturer och lastinkapsling In Vitro

Article DOI: 10.3791/60935-v • 10:01 min • April 8th, 2020
April 8th, 2020 •
*1,2, *1,2, 1,2, 1,2, 1,2,3,4,5,6
1Center for Biological Systems Analysis, University of Freiburg, 2Faculty of Biology, University of Freiburg, 3Freiburg Institute for Advanced Studies (FRIAS), University of Freiburg, 4BIOSS Centre for Biological Signalling Studies, University of Freiburg, 5IMTEK Department of Microsystems Engineering, University of Freiburg, 6Cluster of Excellence livMatS at FIT - Freiburg Center for Interactive Materials and Bioinspired Technologies, University of Freiburg
* These authors contributed equally

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I gränssnittet mellan organiska och vattenhaltiga lösningsmedel samlas skräddarsydda amphifila elastinliknande proteiner till komplexa supramolekylära strukturer som blåsor, fibrer och coacervater som utlöses av miljöparametrar. De beskrivna monteringsprotokollen ger proteinmembranbaserade fack (PMBCs) med avstämbara egenskaper, vilket möjliggör inkapsling av olika laster.

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Kemi Nummer 158 elastinliknande proteiner proteinbaserade blåsor proteinfibrer läkemedelstillförselsystem självmontering proteinmembran
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