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Saccharose præference og nyhed-induceret hypofagi test hos rotter ved hjælp af en automatiseret fødeindtagelse overvågningssystem
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Saccharose præference og nyhed-induceret hypofagi test hos rotter ved hjælp af en automatiseret fødeindtagelse overvågningssystem

Article DOI: 10.3791/60953-v • 07:33 min • May 8th, 2020
May 8th, 2020 •
*1, *1, 1, 1, 1, 1,2,3, 1,4, 1,3
1Charité Center for Internal Medicine and Dermatology, Department for Psychosomatic Medicine, Charité-Universitätsmedizin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 2Department of Internal Medicine, Helios Clinic, 3Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, 4Department of Quantitative Health Sciences, University of Massachusetts Medical School
* These authors contributed equally

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Præsenteret her er en protokol til at studere depression-lignende og anhedonic adfærd hos rotter. Det kombinerer to veletablerede adfærdsmæssige metoder, saccharose præference og nyhed-induceret hypofagi test, med en automatiseret mad og væskeindtag overvågningssystem, at indirekte undersøge gnaver adfærd ved hjælp af surrogat parametre.

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Medicin anhedonia test dyremodel adfærd depression automatiseret mad og flydende indtag system rotter
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