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JoVE Journal Neuroscience
Translaminares autonomes Systemmodell zur Modulation des intraokularen und intrakraniellen Drucks in menschlichen spenderseitigen Segmenten
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Translaminares autonomes Systemmodell zur Modulation des intraokularen und intrakraniellen Drucks in menschlichen spenderseitigen Segmenten

Article DOI: 10.3791/61006-v • 08:55 min • April 24th, 2020
April 24th, 2020 •
1, 1, 2, 3
1North Texas Eye Research Institute, Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, 2Mechanical Engineer Consultant, 3Department of Ophthalmology and Visual Sciences, School of Medicine and Public Health, University of Wisconsin

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Wir beschreiben und beschreiben die Verwendung des translaminaren autonomen Systems. Dieses System nutzt das menschliche hintere Segment, um den Druck innerhalb des Segments (intraokular) und um den Sehnerv (intrakranial) unabhängig zu regulieren, um einen translaminaren Druckgradienten zu erzeugen, der Merkmale der glaukomatösen Optikusneuropathie nachahmt.

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Neuroscience Augeninnendruck intrakranieller Druck translaminarer Druckgradient retinale Ganglienzellen Sehnervenkopf Perfusionsorgankultur
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