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Journal / Bioengineering / Makromoleküler Kalabalık Kullanılarak İnsan…
JoVE Journal
Bioengineering

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JoVE Journal Bioengineering
Makromoleküler Kalabalık Kullanılarak İnsan Kutanöz Hipertrofik YaraNın In Vitro Modeli
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Makromoleküler Kalabalık Kullanılarak İnsan Kutanöz Hipertrofik YaraNın In Vitro Modeli

Article DOI: 10.3791/61037-v • 08:20 min • May 1st, 2020
May 1st, 2020 •
1, 1, 1, 1, 1,2, 1, 1,3, 1
1Skin Research Institute of Singapore, Agency for Science, Technology and Research (A*STAR), 2School of Chemical and Life Sciences, Singapore Polytechnic, 3Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR)

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Bu protokol, in vivo koşullarına benzeyen bir in vitro insan hipertrofik skar dokusu modeli oluşturmak için makromoleküler kalabalık kullanımını açıklar. Kalabalık bir makromoleküler ortamda ekili zaman, insan deri fibroblastlar fenotipleri, biyokimya, fizyoloji ve skar dokusu andıran fonksiyonel özellikleri sergiler.

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Biyomühendislik Sayı 159 hipertrofik skar fibroblastlar makromoleküler kalabalık kollajen hücre dışı matriks yoğunluk gradyan orta polivinilpyrrolidone
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