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Journal / Biochemistry / Dechiffrera de strukturella effekterna av att…
JoVE Journal
Biochemistry

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JoVE Journal Biochemistry
Dechiffrera de strukturella effekterna av att aktivera EGFR somatiska mutationer med molekylär dynamik Simulering
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Dechiffrera de strukturella effekterna av att aktivera EGFR somatiska mutationer med molekylär dynamik Simulering

Article DOI: 10.3791/61125-v • 15:05 min • May 20th, 2020
May 20th, 2020 •
1, 2, 2,3,4, 1
1Structural Bioinformatics Laboratory, Biochemistry, Faculty of Science and Engineering, Åbo Akademi University, 2Medicity Research Laboratories and Institute of Biomedicine, University of Turku, 3Turku Bioscience Centre, University of Turku and Åbo Akademi University, 4Department of Oncology and Radiotherapy, University of Turku and Turku University Hospital

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Målet med detta protokoll är att använda molekylärdynamiksimuleringar för att undersöka de dynamiska strukturella förändringar som sker på grund av aktiverande mutationer av EGFR-kinasproteinet.

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Denna månad i JoVE Molekylär dynamik simuleringar Proteinstruktur analyser Epidermal tillväxtfaktor receptor familj Somatiska mutationer Cancer
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