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Caenorhabditis elegans de novo Protein Sentez Oranlarının Değerlendirilmesi
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Caenorhabditis elegans de novo Protein Sentez Oranlarının Değerlendirilmesi

Article DOI: 10.3791/61170-v • 06:27 min • September 12th, 2020
September 12th, 2020 •
*1,2, *1,2, 1,2
1Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, Greece, 2Department of Basic Sciences, Faculty of Medicine, University of Crete, Heraklion, 70013, Crete, Greece
* These authors contributed equally

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Burada, de novo protein sentezini in vivo değerlendirmek için, fotobeyazrlama (FRAP) sonrası nematod Caenorhabditis elegans ve floresan kurtarma kullanan radyoaktif olmayan ve noninvaziv bir yöntem sınıyoruz ve tanımlıyoruz. Bu yöntem, protein sentezinin yeni modülatörlerini belirlemek için genetik ve/veya farmakolojik ekranlar ile kombine edilebilir.

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Biyoloji Sayı 163 Yaşlanma FRAP Homeostaz Fotobeyazrlama Protein sentezi Proteostaz
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