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Immunology and Infection

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JoVE Journal Immunology and Infection
Begeleide machine learning voor semi-kwantificering van extracellulair DNA in Glomerulonephritis
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Begeleide machine learning voor semi-kwantificering van extracellulair DNA in Glomerulonephritis

Article DOI: 10.3791/61180-v • 09:16 min • June 18th, 2020
June 18th, 2020 •
1, 2, 1, 1,3
1Department of Medicine, Monash University, 2Monash Micro Imaging, Monash University, 3Immunology Department, Monash Health

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Extracellulair DNA (ecDNA) dat vrijkomt bij de celdood is pro-inflammatorium en draagt bij aan ontsteking. Meting van ecDNA op de plaats van letsel kan de werkzaamheid van therapeutische behandeling in het doelorgaan bepalen. Dit protocol beschrijft het gebruik van een machine learning tool om de meting van ecDNA in nierweefsel te automatiseren.

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Immunologie en infectie Probleem 160 Glomerulonephritis Extracellulair DNA Nier Celdood Supervised Machine Learning
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