JoVE Journal
Neuroscience
Neuroscience
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げっ歯類における血液脳関門開口のためのハイスループット画像誘導定型神経ナビゲーションと集中超音波システム
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Article
DOI:
10.3791/61269-v
•
08:02 min
•
July 16th, 2020
げっ歯類における血液脳関門開口のためのハイスループット画像誘導定型神経ナビゲーションと集中超音波システム
July 16th, 2020
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Rianne Haumann*1,2, Elvin ’t Hart*2, Marc P. P. Derieppe2, Helena C. Besse3, Gertjan J. L. Kaspers1,2, Eelco Hoving2, Dannis G. van Vuurden1,2, Esther Hulleman1,2, Mario Ries3
1Amsterdam UMC, Vrije Universiteit Amsterdam, Pediatric Oncology, Cancer Center Amsterdam, 2Princess Máxima Center for Pediatric Oncology, 3Imaging Division, Utrecht University
* These authors contributed equally
Summary
Please note that all translations are automatically generated.
Click here for the English version.
血液脳関門(BBB)は、マイクロバブル媒介性集中超音波(FUS)で一時的に破壊することができる。ここでは、非超音波専門家がアクセス可能なモジュラーFUSシステムを使用して、高スループットBBBのインビボでの開口のためのステップバイステッププロトコルについて説明する。