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JoVE Journal Neuroscience
En high-throughput Image-Guided Stereotactic Neuronavigation og fokuseret ultralyd system til blod-hjerne barrieren Åbning i gnavere
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En high-throughput Image-Guided Stereotactic Neuronavigation og fokuseret ultralyd system til blod-hjerne barrieren Åbning i gnavere

Article DOI: 10.3791/61269-v • 08:02 min • July 16th, 2020
July 16th, 2020 •
*1,2, *2, 2, 3, 1,2, 2, 1,2, 1,2, 3
1Amsterdam UMC, Vrije Universiteit Amsterdam, Pediatric Oncology, Cancer Center Amsterdam, 2Princess Máxima Center for Pediatric Oncology, 3Imaging Division, Utrecht University
* These authors contributed equally

Summary
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Blod-hjerne barrieren (BBB) kan midlertidigt forstyrres med mikroboble-medieret fokuseret ultralyd (FUS). Her beskriver vi en trinvis protokol for BBB-åbning i høj overførselshastighed ved hjælp af et modulært FUS-system, der er tilgængeligt for ikke-ultralydseksperter.

Tags

Neurovidenskab Problem 161 Høj-gennemløb workflow fokuseret ultralyd medicin levering image-guidet sonoporation blod-hjerne barriere
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