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Análise do fenótipo esquelético de um modelo de rato de exclusão stat3 condicional
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Análise do fenótipo esquelético de um modelo de rato de exclusão stat3 condicional

Article DOI: 10.3791/61390-v • 08:42 min • July 3rd, 2020
July 3rd, 2020 •
*1, *2, 1, 1, 1, 1, 3, 1
1Center of Craniofacial Orthodontics, Department of Oral and Cranio-maxillofacial Science, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, National Clinical Research center of Stomatology, 2Department of Stomatology, Dalian Medical University, 3The 2nd Dental Center, Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai Key Laboratory of Stomatology & Shanghai Research Institute of Stomatology, National Clinical Research center of Stomatology
* These authors contributed equally

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Este protocolo descreve um método canônico para entender os genes críticos que controlam a atividade osteoclasta in vivo. Este método utiliza um modelo de camundongo transgênico e algumas técnicas canônicas para analisar o fenótipo esquelético.

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Biologia Edição 161 fenótipo esquelético metabolismo ósseo rotulagem osteoclastos STAT3 camundongos transgênicos
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