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Journal / Immunology and Infection / Stabilità e struttura del pipistrello Maggiore…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Stabilità e struttura del pipistrello Maggiore Istocompatibilità Complesso Classe I con Eterolologo β2-Microglobulina
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Stabilità e struttura del pipistrello Maggiore Istocompatibilità Complesso Classe I con Eterolologo β2-Microglobulina

Article DOI: 10.3791/61462-v • 11:17 min • March 10th, 2021
March 10th, 2021 •
*1,2, *3,4, *2,5, 1,2, 1,2, 2, 2, 4, 1, 4, 1,2
1School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, 2NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, 3Faculty of Health Sciences, University of Macau, 4CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, 5Savaid Medical School, University of Chinese Academy of Sciences
* These authors contributed equally

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Il protocollo descrive metodi sperimentali per ottenere sostituzioni stabili del complesso di istocompatibilità maggiore (MHC) classe Iattraversopotenziali sostituzioni di β 2-microglobulina (β2m) da diverse specie. Sono stati studiati il confronto strutturale dell'MHC I stabilizzato da β omologo edeterologodi 2 m.

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Immunologia e infezione Numero 169 Principali molecole di classe I del complesso antigene di istocompatibilità (MHC) struttura complessa di β2-microglobulina (β2m) peptide TCR tetramero
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