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Journal / Immunology and Infection / 異種β…
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Immunology and Infection

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JoVE Journal Immunology and Infection
異種β 2-ミクログロブリンを有するコウモリ主要組織適合性複合体クラスIの安定性と構造
Efficient SARS-CoV-2 Quantitative Reverse Transcriptase PCR Saliva Diagnostic Strategy utilizing Open-Source Pipetting Robots
Journal (Immunology and Infection)
Efficient SARS-CoV-2 Quantitative Reverse Transcriptase PCR Saliva Diagnostic Strategy utilizing Open-Source Pipetting Robots
Femur Window Chamber Model for In Vivo Cell Tracking in the Murine Bone Marrow
Journal (Immunology and Infection)
Femur Window Chamber Model for In Vivo Cell Tracking in the Murine Bone Marrow
 
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異種β 2-ミクログロブリンを有するコウモリ主要組織適合性複合体クラスIの安定性と構造

Article DOI: 10.3791/61462-v • 11:17 min • March 10th, 2021
March 10th, 2021 •
*1,2, *3,4, *2,5, 1,2, 1,2, 2, 2, 4, 1, 4, 1,2
1School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, 2NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, 3Faculty of Health Sciences, University of Macau, 4CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, 5Savaid Medical School, University of Chinese Academy of Sciences
* These authors contributed equally

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Summary
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プロトコルは、異なる種からの2-ミクログロブリン(β 2m)置換 βの可能性を通じて安定な主要組織適合性複合体(MHC)クラスIを得るための実験的方法を記述する。2mの相同と異種βにより安定化したMHCIの構造比較を検討した。

Tags

免疫学と感染症,課題169,主要組織適合性抗原複合体(MHC)クラスI分子、β 2-ミクログロブリン(β 2m)複合構造、ペプチド、TCR、四トラマー
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