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Single Myofiber isolasjon og kultur fra en murin modell av Emery-Dreifuss muskeldystrofi i tidlig post-natal utvikling
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Single Myofiber isolasjon og kultur fra en murin modell av Emery-Dreifuss muskeldystrofi i tidlig post-natal utvikling

Article DOI: 10.3791/61516-v • 08:07 min • July 1st, 2020
July 1st, 2020 •
1,2, 1,2, 3, 1,2,4
1Istituto Nazionale di Genetica Molecolare "Romeo ed Enrica Invernizzi", 2IRCCS Santa Lucia Foundation, 3Department of Biology and Biotechnology, "C. Darwin" Sapienza University, CNR - IBPM, 4CNR – Institute of Biomedical Technologies (ITB)

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Her foreslår vi en metode for effektivt å få enkeltmuskelfibre på tidlige postnatal utviklingsstadier fra homozygot mutant Lamin Δ8-11 mus modell, en svært alvorlig modell for Emery-Dreifuss muskeldystrofi (EDMD).

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Medisin Utgave 161 Emery-Dreifuss muskeldystrofi mus modell myofiber immunofluorescens satellitt muskel stamceller differensiering muskel regenerering
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