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Journal / Bioengineering / Lindring av blodburna cellen bilaga till…
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Bioengineering

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JoVE Journal Bioengineering
Lindring av blodburna cellen bilaga till metallimplantat genom CD47-derived Peptide Immobilization
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Lindring av blodburna cellen bilaga till metallimplantat genom CD47-derived Peptide Immobilization

Article DOI: 10.3791/61545-v • 08:13 min • December 3rd, 2020
December 3rd, 2020 •
1, 1, 1,2, 1,2, *1,2, *1,2
1The Children's Hospital of Philadelphia, 2Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania
* These authors contributed equally

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Presenteras här är ett protokoll för appending peptid CD47 (pepCD47) till metall stent med hjälp av polybisfosfonat kemi. Funktionalisering av metallstent med hjälp av pepCD47 förhindrar fastsättning och aktivering av inflammatoriska celler därmed förbättra deras biokompatibilitet.

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Bioengineering Utgåva 166 ytfunktionalisering metall implantat stent CD47 inflammation trombos peptider bioconjugation
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