Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
JoVE Journal
Cancer Research

This content is Open Access.

使用转录组学分析绘制无序致癌转录因子的结构-功能关系
 
Click here for the English version

使用转录组学分析绘制无序致癌转录因子的结构-功能关系

Article DOI: 10.3791/61564-v 09:58 min June 27th, 2020
June 27th, 2020

Chapters

Summary

Please note that all translations are automatically generated.

Click here for the English version.

内在无序结构域对致癌融合转录因子功能很重要。为了治疗靶向这些蛋白质,需要更详细地了解这些结构域所采用的调节机制。在这里,我们使用转录组学来绘制尤文氏肉瘤中内在无序的EWS结构域的重要结构特征。

Tags

癌症研究,第160期,转录组学,RNA-seq,结构功能,转录因子,内在无序结构域,EWS / FLI,尤文氏肉瘤,基因调控
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter