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Observación microscópica de la dinámica de linfocitos en los parches de Rat Peyer
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Observación microscópica de la dinámica de linfocitos en los parches de Rat Peyer

Article DOI: 10.3791/61568-v • 06:37 min • June 25th, 2020
June 25th, 2020 •
1,2, 1, 2, 1, 2, 1
1Department of internal medicine, National Defense Medical College, 2Division of Gastroenterology and Hepatology, Department of Internal Medicine, Jikei University School of Medicine

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Aquí, describimos un método preciso para recoger linfocitos de conductos torácicos y observar la migración de linfocitos trópicos intestinales en parches de rata Peyer durante 3 horas utilizando fotografía de lapso de tiempo. Esta técnica puede aclarar cómo la dinámica de los linfocitos se ve afectada en condiciones inflamatorias.

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Medicamento Número 160 2-accetyl-4-tetrahidroxibutyl imidazol (THI) esfiingosina-1-fosfato (S1P) liasa S1P (SPL) parches de Peyer (PPs) venules endoteliales altas (HEV) migración de linfocitos
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