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Journal / Neuroscience / GM-fri generering av blodavledede nevronceller
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JoVE Journal Neuroscience
GM-fri generering av blodavledede nevronceller
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GM-fri generering av blodavledede nevronceller

Article DOI: 10.3791/61634-v • 08:11 min • February 13th, 2021
February 13th, 2021 •
1, 1, 2, 2
1ACA CELL Biotech GmbH, 2Departmento Ciencias Biomedicas, Universidad Cardenal Herrera-CEU

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Vi presenterer en genetisk modifisert-fri (GM-fri) metode for å skaffe celler med en nevronal fenotype fra omprogrammerte perifere blodlegemer. Aktivering av en signalvei knyttet til nytt humant GPI-tilknyttet protein avslører en effektiv GM-fri metode for å skaffe menneskelige pluripotente stamceller.

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Nevrovitenskap Utgave 168 Perifert blod omprogrammering signalering pluripotente stamceller nevrale stamceller og celleerstatningsterapier
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