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Un ensayo ex vivo de brotes de coroides de angiogénesis microvascular ocular

Article DOI: 10.3791/61677-v • 06:10 min • August 6th, 2020
August 6th, 2020 •
1, 2, 1, 1, 1,3, 1
1Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, 2Department of Clinical and Metabolic Genetics, Hospital for Sick Children, University of Toronto, 3Manton Center for Orphan Disease, Harvard Medical School, Boston Children's Hospital

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Este protocolo presenta el ensayo de brotación coroides, un modelo ex vivo de proliferación microvascular. Este ensayo se puede utilizar para evaluar las vías implicadas en la proliferación de micro vasos corooidales y evaluar los tratamientos farmacológicos utilizando tejido de ratón de tipo salvaje y modificado genéticamente.

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Biología Número 162 ensayo de brotes de coroides células endoteliales epitelio pigmentario de la retina RPE angiogénesis coroidal neovascularización coroidal degeneración macular relacionada con la edad AMD ex vivo
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