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En ortotopisk reseksjonell musemodell av kreft i bukspyttkjertelen
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En ortotopisk reseksjonell musemodell av kreft i bukspyttkjertelen

Article DOI: 10.3791/61726-v • 07:17 min • September 24th, 2020
September 24th, 2020 •
1,2,4,5, 1,2, 1,2, 1,2, 3, 1, 1,2, 1,2, 1,2
1Pancreatic Research Group, South Western Sydney Clinical School, University of New South Wales, 2Ingham Institute for Applied Medical Research, 3Centre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 4Surgical Innovations Unit, Westmead Hospital, 5Westmead Clinical School, University of Sydney

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I klinisk sammenheng vil pasienter med lokalisert kreft i bukspyttkjertelen gjennomgå pankreatektomi etterfulgt av adjuvant behandling. Denne protokollen rapportert her tar sikte på å etablere en sikker og effektiv metode for modellering av dette kliniske scenariet hos nakne mus, gjennom ortotopisk implantasjon av bukspyttkjertelkreft etterfulgt av distal pankreatektomi og praktektomi.

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Kreftforskning Utgave 163 Bukspyttkjertelkanal adenokarsinom (PDAC) Adjuvant terapi Neoadjuvant terapi Pankreatektomi Ortopisk musemodell Bukspyttkjertel stellate celler
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