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JoVE Journal Cancer Research
Un modelo ortotópico de ratón reseccional de cáncer de páncreas
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Un modelo ortotópico de ratón reseccional de cáncer de páncreas

Article DOI: 10.3791/61726-v • 07:17 min • September 24th, 2020
September 24th, 2020 •
1,2,4,5, 1,2, 1,2, 1,2, 3, 1, 1,2, 1,2, 1,2
1Pancreatic Research Group, South Western Sydney Clinical School, University of New South Wales, 2Ingham Institute for Applied Medical Research, 3Centre for Circulating Tumour Cell Diagnostics and Research, Ingham Institute for Applied Medical Research, 4Surgical Innovations Unit, Westmead Hospital, 5Westmead Clinical School, University of Sydney

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En el contexto clínico, los pacientes con cáncer de páncreas localizado se someterán a pancreatectomía seguida de tratamiento adyuvante. Este protocolo divulgado aquí apunta establecer un método seguro y de manera efectiva de modelar este escenario clínico en ratones desnudos, con la implantación orthotopic del cáncer pancreático seguido por pancreatectomy y splenectomy distales.

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Investigación del cáncer edición 163 adenocarcinoma ductal pancreático (PDAC) terapia ayudante terapia neoadyuvante pancreatectomy modelo orthotopic del ratón células estrelladas pancreáticas
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