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JoVE Journal Biology
Systematisk tilgang til identificering af nye antimikrobielle og antibiofilmmolekyler fra planternes ekstrakter og fraktioner for at forhindre caries
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Systematisk tilgang til identificering af nye antimikrobielle og antibiofilmmolekyler fra planternes ekstrakter og fraktioner for at forhindre caries

Article DOI: 10.3791/61773-v • 08:20 min • March 31st, 2021
March 31st, 2021 •
*1, *1, *2, 2,3, 2, 1
1Department of Dental Materials and Prosthodontics, School of Dentistry, São Paulo State University (UNESP), 2Department of Organic Chemistry, Institute of Chemistry, São Paulo State University (UNESP), 3Faculty of Pharmaceutical Sciences of Ribeiraão Preto (FCFRP-USP), Department of Physics and Chemistry, University of São Paulo
* These authors contributed equally

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Naturlige produkter udgør lovende udgangspunkter for udviklingen af nye lægemidler og terapeutiske midler. Men på grund af den høje kemiske mangfoldighed er det en udfordrende og tidskrævende opgave at finde nye terapeutiske forbindelser fra planter. Vi beskriver en forenklet tilgang til identifikation af antimikrobielle og antibiofilmmolekyler fra planteekstrakter og fraktioner.

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Biologi Mikrobiologi biofilm naturlige produkter mutans streptokokker antimikrobielle stoffer caries lægemiddelforskning biologiske tilgange
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