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Journal / Cancer Research / Caenorhabditis elegans를 사용하여 EGFR 및 RAS 억제제의…
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Cancer Research

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JoVE Journal Cancer Research
Caenorhabditis elegans를 사용하여 EGFR 및 RAS 억제제의 식별
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Caenorhabditis elegans를 사용하여 EGFR 및 RAS 억제제의 식별

Article DOI: 10.3791/61788-v • 08:12 min • October 5th, 2020
October 5th, 2020 •
1,2, 1, 1, 1, 2, 1
1Department of Diagnostic and Biomedical Sciences, School of Dentistry, University of Texas Health Science Center, 2Department of Integrative Biology and Pharmacology, McGovern Medical School, University of Texas Health Science Center

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유전적으로 통할 수 있는 선충성 Caenorhabditis elegans는 약물 발견을 위한 간단하고 저렴한 모델로 사용될 수 있습니다. 여기에 설명된 RAS 및 EGFR 단백질의 하류 신호를 억제하는 항암 치료제를 식별하는 프로토콜이 있다.

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암 연구 문제 164 케노르하비티스 엘레간스 LET-60 LET-23 K-RAS EGFR GFP
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