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Journal / Bioengineering / Cultivando uma Epiderme Humana Reconstruída…
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Bioengineering

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JoVE Journal Bioengineering
Cultivando uma Epiderme Humana Reconstruída Tridimensional em grande escala
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Cultivando uma Epiderme Humana Reconstruída Tridimensional em grande escala

Article DOI: 10.3791/61802-v • 08:49 min • May 28th, 2021
May 28th, 2021 •
1, 1,2, 3, 3,4, 1, 2
1Adolphe Merkle Institute, University of Fribourg, 2Dow Silicones Belgium SRL, 3Department of Biomedical and Specialist Surgical Sciences, University of Ferrara, 4Department of Animal Sciences, Plants for Human Health Institute, North Carolina State University

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Este protocolo descreve um método simples para cultivar epiderme humana reconstituída tridimensional de forma reprodutível e robusta. Além disso, caracteriza a relação estrutura-função do modelo de barreira epidérmica. Também são apresentadas as respostas biológicas da epiderme humana reconstituída sobre estímulos proinflamatórios.

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Bioengenharia Edição 171 Epiderme humana reconstituída equivalentes epidérmicos humanos queratinócitos primários epiderme estudos in vitro.
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