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JoVE Journal Immunology and Infection
Procedimientos de trasplante de médula ósea en ratones para estudiar la hematopoyesis clonal
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Procedimientos de trasplante de médula ósea en ratones para estudiar la hematopoyesis clonal

Article DOI: 10.3791/61875-v • 08:00 min • May 26th, 2021
May 26th, 2021 •
1, 4, 4, 4, 4, 4, 2, 3,4, 1,4
1Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, 2Department of Cardiology, Xinqiao Hospital, Army Medical University, 3Department of Cardiology, Osaka City University Graduate School of Medicine, 4Hematovascular Biology Center, Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine

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Describimos tres métodos de trasplante de la médula (BMT): BMT con la irradiación de cuerpo entero, BMT con la irradiación blindada, y método de BMT sin el pre-condicionamiento (BMT adoptivo) para el estudio de la hematopoyesis clónica en modelos del ratón.

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Inmunología e Infección Número 171 hematopoyesis clonal pre-condicionamiento mieloablativo condicionamiento no mieloablativo reconstitución de células hematopoyéticas trasplante de médula ósea transferencia adoptiva
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