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JoVE Journal Cancer Research
Um Modelo de Camundongo para Investigar o Papel de Fibroblastos Associados ao Câncer no Crescimento Tumoral
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Um Modelo de Camundongo para Investigar o Papel de Fibroblastos Associados ao Câncer no Crescimento Tumoral

Article DOI: 10.3791/61883-v • 06:35 min • December 22nd, 2020
December 22nd, 2020 •
1,2, 1,2,3, 1,2, 3, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 1,2, 3, 1,2, 1,2, 1,2,4, 1,2, 1,2,4
1Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, 2Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, 3Department of Molecular Biology, Princeton University, 4Molecular Biology Institute, University of California, Los Angeles

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Um protocolo para co-injetar células cancerosas e fibroblastos e monitorar o crescimento do tumor ao longo do tempo é fornecido. Este protocolo pode ser utilizado para entender as bases moleculares do papel dos fibroblastos como reguladores do crescimento tumoral.

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Cancer Research Fibroblastos associados ao câncer xenoenxerto melanoma injeção intradérmica ortotópico microambiente tumoral
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