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Journal / Genetics / 将人类成纤维细胞直接重新编程到肌细胞中，以研究神经肌肉疾病的治疗方法…
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JoVE Journal Genetics
将人类成纤维细胞直接重新编程到肌细胞中，以研究神经肌肉疾病的治疗方法
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将人类成纤维细胞直接重新编程到肌细胞中，以研究神经肌肉疾病的治疗方法

Article DOI: 10.3791/61991-v • 10:28 min • April 3rd, 2021
April 3rd, 2021 •
1, 1, 1, 2, 2,3,4,6, 5, 1,6, 1,6
1Center for Gene Therapy, The Research Institute at Nationwide Children’s Hospital, 2Center for Cardiovascular Research, The Research Institute at Nationwide Children’s Hospital, 3The Heart Center, Nationwide Children’s Hospital, 4Division of Genetic and Genomic Medicine, Nationwide Children’s Hospital, 5Department of Human Genetics, The University of Utah School of Medicine, 6Department of Pediatrics, The Ohio State University

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此协议描述了皮肤成纤维细胞转化为肌细胞及其分化成肌管。细胞系来自神经肌肉疾病患者，可用于研究病理机制和测试治疗策略。

Tags

遗传学， 问题 170， 重新编程， htert， 肌病， 成纤维细胞， 肌细胞， 神经肌肉疾病， 治疗测试
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