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Journal / Cancer Research / Un modello murino di ommaya xenotrapianto per…
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Cancer Research

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JoVE Journal Cancer Research
Un modello murino di ommaya xenotrapianto per studiare la terapia mirata diretta della malattia leptomeningea
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Un modello murino di ommaya xenotrapianto per studiare la terapia mirata diretta della malattia leptomeningea

Article DOI: 10.3791/62033-v • 07:17 min • January 29th, 2021
January 29th, 2021 •
1,2, 3, 4, 4, 1, 5, 6, 7, 4, 2, 1,2
1Department of Neuro-Oncology, H. Lee Moffitt Cancer Center & Research Institute, 2Department of Tumor Biology, H. Lee Moffitt Cancer Center & Research Institute, 3Department of Comparative Medicine, University of South Florida, 4Department of Breast Oncology, H. Lee Moffitt Cancer Center & Research Institute, 5Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, 6Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, 7Department of Medical Oncology, Roswell Park Comprehensive Cancer Center

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Qui, descriviamo un modello di xenotrapianto murino che assomiglia funzionalmente a un serbatoio di Ommaya nei pazienti. Abbiamo sviluppato il Murine Ommaya per studiare nuove terapie per la malattia leptomeningea universalmente fatale.

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Cancer Research Malattia leptomeningea modelli sperimentali modello murino serbatoio murino Ommaya
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