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JoVE Journal
Cancer Research

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使用快速和定量的细胞内胆碱膜模型发现转移调节器
 
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使用快速和定量的细胞内胆碱膜模型发现转移调节器

Article DOI: 10.3791/62077-v 07:03 min February 3rd, 2021
February 3rd, 2021

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Summary

Please note that all translations are automatically generated.

Click here for the English version.

这是一种有效的方法来筛选抑制剂或癌症转移的驱动因素。细胞,用表达库转导,被注射到鸡胆碱膜血管,形成转移菌落。已降低或增加侵入性的菌落被切除、扩大、重新注入以确认其表型,最后使用高吞吐量测序进行分析。

Tags

癌症研究,第168期,癌症转移,胆管兰托膜,紧凑型菌落,活体内筛查,活体成像,侵入性转移性聚落,转移抑制剂
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