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Journal / Genetics / In-Nucleus Hi-C i Drosophila-celler
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In-Nucleus Hi-C i Drosophila-celler

Article DOI: 10.3791/62106-v • 11:58 min • September 15th, 2021
September 15th, 2021 •
1, 1, 1, 1
1Departamento de Genética Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México

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Genomet er organisert i atomrommet i forskjellige strukturer som kan avsløres gjennom kromosomkonformasjonsfangstteknologier. Hi-C-metoden i kjernen gir en genomomfattende samling av kromatininteraksjoner i Drosophila-cellelinjer, som genererer kontaktkart som kan utforskes med megabaseoppløsning på begrensningsfragmentnivå.

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Genetikk Utgave 175 Kromatin Genome 3D-organisasjon rom topologisk assosierende domener
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