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In-Nucleus Hi-C i Drosophila Cells
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In-Nucleus Hi-C i Drosophila Cells

Article DOI: 10.3791/62106-v • 11:58 min • September 15th, 2021
September 15th, 2021 •
1, 1, 1, 1
1Departamento de Genética Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México

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Genomet er organiseret i det nukleare rum i forskellige strukturer, der kan afsløres gennem kromosom kropsbygningsfangstteknologier. In-nucleus Hi-C-metoden giver en genomdækkende samling af chromatininteraktioner i Drosophila-cellelinjer, som genererer kontaktkort, der kan udforskes ved megabaseopløsning på begrænsningsfragmentniveau.

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Genetik Chromatin Genome 3D organisation rum topologisk forbinder domæner
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