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Genetics

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In-Nucleus Hi-C i Drosophila Cells
 
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In-Nucleus Hi-C i Drosophila Cells

Article DOI: 10.3791/62106-v
September 15th, 2021

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Summary September 15th, 2021

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Genomet er organiseret i det nukleare rum i forskellige strukturer, der kan afsløres gennem kromosom kropsbygningsfangstteknologier. In-nucleus Hi-C-metoden giver en genomdækkende samling af chromatininteraktioner i Drosophila-cellelinjer, som genererer kontaktkort, der kan udforskes ved megabaseopløsning på begrænsningsfragmentniveau.

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