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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction

Article DOI: 10.3791/62167-v • 09:20 min • February 13th, 2021
February 13th, 2021 •
*1,2, *1, 1,2,3
1Institute for Medical Engineering and Science, Massachusetts Institute of Technology, 2Health Science and Technology Program, Harvard/Massachusetts Institute of Technology, 3Department of Mechanical Engineering, Massachusetts Institute of Technology
* These authors contributed equally

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Summary
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This work introduces two computational models of heart failure with preserved ejection fraction based on a lumped-parameter approach and finite element analysis. These models are used to evaluate the changes in the hemodynamics of the left ventricle and related vasculature induced by pressure overload and diminished ventricular compliance.

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Lumped-Parameter Modeling Finite Element Modeling Heart Failure With Preserved Ejection Fraction Cardiovascular Hemodynamics Acute Pressure Load Chronic Loss Of Ventricular Compliance Computational Efficiency Financial Amount Approach Accurate Modeling Effective Treatments EFPEF Computational Methods Medical Devices Therapeutics Numerical Solver Environment Hydraulics Library Hydraulic Pipeline Elements Wall Compliance Fluid Compressibility Linear Resistance Elements Contractility Of Heart Chambers Custom Variable Compliance Chamber Element Time Varying User Defined Input Signal Physical Signal Repeating Sequence Element
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