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Neuroscience
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JoVE Journal Neuroscience
Analyse av cerebral vasospasme i en murine modell av subarachnoid blødning med høyfrekvent transkraniell dupleks ultralyd
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Analyse av cerebral vasospasme i en murine modell av subarachnoid blødning med høyfrekvent transkraniell dupleks ultralyd

Article DOI: 10.3791/62186-v • 10:41 min • June 3rd, 2021
June 3rd, 2021 •
*1, *2,3,4, *1, 1, 2,3,4, 2,3,4, 5, 1, 5
1Department of Neurosurgery, University Medical Center of the Johannes Gutenberg-University of Mainz, 2Center for Cardiology - Cardiology I, University Medical Center of the Johannes Gutenberg-University of Mainz, 3Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg-University of Mainz, 4German Center for Cardiovascular Research (DZHK) - Partner site Rhine-Main, 5Department of Anesthesiology, University Medical Center of the Johannes Gutenberg-University of Mainz
* These authors contributed equally

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Målet med dette manuskriptet er å presentere en sonografibasert metode som tillater in vivo-avbildning av blodstrømmen i cerebral arterier hos mus. Vi demonstrerer dens anvendelse for å bestemme endringer i blodstrømshastigheter forbundet med vasospasme i murinmodeller av subarachnoid blødning (SAH).

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Tilbaketrekning Utgave 172 Subarachnoid blødning musemodell liten dyremodell langsgående studie reduksjonsstrategi transkraniell Doppler sonografi transkraniell fargekodet Duplex sonografi høyfrekvent ultralyd vasospasme cerebral vasospasme forsinket cerebral iskemi tidlig hjerneskade
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