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Journal / Neuroscience / Análise do Vasospasmo Cerebral em um Modelo…
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JoVE Journal Neuroscience
Análise do Vasospasmo Cerebral em um Modelo Murine de Hemorragia Subaracnóide com Ultrassom Duplex Transcranial de Alta Frequência
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Análise do Vasospasmo Cerebral em um Modelo Murine de Hemorragia Subaracnóide com Ultrassom Duplex Transcranial de Alta Frequência

Article DOI: 10.3791/62186-v • 10:41 min • June 3rd, 2021
June 3rd, 2021 •
*1, *2,3,4, *1, 1, 2,3,4, 2,3,4, 5, 1, 5
1Department of Neurosurgery, University Medical Center of the Johannes Gutenberg-University of Mainz, 2Center for Cardiology - Cardiology I, University Medical Center of the Johannes Gutenberg-University of Mainz, 3Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg-University of Mainz, 4German Center for Cardiovascular Research (DZHK) - Partner site Rhine-Main, 5Department of Anesthesiology, University Medical Center of the Johannes Gutenberg-University of Mainz
* These authors contributed equally

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O objetivo deste manuscrito é apresentar um método baseado em sonografia que permita imagens in vivo do fluxo sanguíneo em artérias cerebrais em camundongos. Demonstramos sua aplicação para determinar alterações nas velocidades de fluxo sanguíneo associadas ao vasospasmo em modelos murinos de hemorragia subaracnóide (SAH).

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Retração Questão 172 Hemorragia Subaracnóide modelo de camundongo modelo animal pequeno estudo longitudinal estratégia de redução sonografia do doppler transcranial sonografia duplex codificada por cores transcranais ultrassom de alta frequência vasospasmo vasospasmo cerebral isquemia cerebral retardada lesão cerebral precoce
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