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Journal / Neuroscience / Мультиплексированный анализ экспрессии генов…
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Neuroscience

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JoVE Journal Neuroscience
Мультиплексированный анализ экспрессии генов сетчатки и доступности хроматина с использованием scRNA-Seq и scATAC-Seq
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Мультиплексированный анализ экспрессии генов сетчатки и доступности хроматина с использованием scRNA-Seq и scATAC-Seq

Article DOI: 10.3791/62239-v • 06:24 min • March 12th, 2021
March 12th, 2021 •
*1, *1, 1, 1,2,3,4,5,6
1Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 2Department of Psychiatry and Behavioral Science, The Johns Hopkins Hospital, 3Department of Ophthalmology, The Johns Hopkins Hospital, 4Department of Neurology, The Johns Hopkins Hospital, 5Institute for Cell Engineering, Johns Hopkins University School of Medicine, 6Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine
* These authors contributed equally

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Здесь авторы демонстрируют полезность MULTI-seq для фенотипирования и последующих пар scRNA-seq и scATAC-seq в характеристике профилей доступности транскриптома и хроматина в сетчатке.

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Неврология Выпуск 169 Развитие Болезнь scRNA-Seq scATAC-Seq MULTI-Seq мультиплекс Хроматин
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