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Neuroscience

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JoVE Journal Neuroscience
Análisis multiplexado de la expresión génica de la retina y la accesibilidad a la cromatina utilizando scRNA-Seq y scATAC-Seq
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Análisis multiplexado de la expresión génica de la retina y la accesibilidad a la cromatina utilizando scRNA-Seq y scATAC-Seq

Article DOI: 10.3791/62239-v • 06:24 min • March 12th, 2021
March 12th, 2021 •
*1, *1, 1, 1,2,3,4,5,6
1Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 2Department of Psychiatry and Behavioral Science, The Johns Hopkins Hospital, 3Department of Ophthalmology, The Johns Hopkins Hospital, 4Department of Neurology, The Johns Hopkins Hospital, 5Institute for Cell Engineering, Johns Hopkins University School of Medicine, 6Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine
* These authors contributed equally

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Aquí, los autores muestran la utilidad de MULTI-seq para fenotipar y posteriormente emparejar scRNA-seq y scATAC-seq en la caracterización de los perfiles de accesibilidad transcriptómica y cromatina en la retina.

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Neurociencia Número 169 Desarrollo Enfermedad scRNA-Seq scATAC-Seq MULTI-Seq multiplex Cromatina
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