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Journal / Neuroscience / Multiplexerad analys av retinal genuttryck och…
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JoVE Journal Neuroscience
Multiplexerad analys av retinal genuttryck och kromatintillgänglighet med hjälp av scRNA-Seq och scATAC-Seq
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Multiplexerad analys av retinal genuttryck och kromatintillgänglighet med hjälp av scRNA-Seq och scATAC-Seq

Article DOI: 10.3791/62239-v • 06:24 min • March 12th, 2021
March 12th, 2021 •
*1, *1, 1, 1,2,3,4,5,6
1Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 2Department of Psychiatry and Behavioral Science, The Johns Hopkins Hospital, 3Department of Ophthalmology, The Johns Hopkins Hospital, 4Department of Neurology, The Johns Hopkins Hospital, 5Institute for Cell Engineering, Johns Hopkins University School of Medicine, 6Kavli Neuroscience Discovery Institute, Johns Hopkins University School of Medicine
* These authors contributed equally

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Här visar författarna nyttan av MULTI-seq för fenotypning och efterföljande parade scRNA-seq och scATAC-seq för att karakterisera de transkriptomiska och kromatin tillgänglighetsprofilerna i näthinnan.

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Neurovetenskap Utgåva 169 Utveckling Sjukdom scRNA-Seq scATAC-Seq MULTI-Seq multiplex Kromatin
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