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Journal / Bioengineering / Farmasötik Keşif için İnsan Retinal…
JoVE Journal
Bioengineering

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JoVE Journal Bioengineering
Farmasötik Keşif için İnsan Retinal Organoidlerinde Toksisite Taramaları
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Farmasötik Keşif için İnsan Retinal Organoidlerinde Toksisite Taramaları

Article DOI: 10.3791/62269-v • 07:45 min • March 4th, 2021
March 4th, 2021 •
1,2, 1,2, 1,2, 1,2
1Lowy Medical Research Institute, 2The Scripps Research Institute

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Burada, olgun insan retinal organoidleri üretmek ve bunları yaşa bağlı retinal dejeneratif hastalık maküler telanjiektazi tip 2 (MacTel) için farmasötik adayları tanımlamak için bir fotoreseptör toksisite testinde kullanmak için adım adım bir protokol sunuyoruz.

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JoVE'de Bu Ay Sayı 169 retinal organoid organoid retina dejenerasyonu MacTel sfingolipid fotoreseptör fenofibrat TÜNEL boyama ilaç taraması lipid toksisitesi
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