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JoVE Journal Cancer Research
Dynamisk billeddannelse af kimære antigenreceptor-T-celler med [18F]tetrafluorborat positronemissionstomografi/computertomografi
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Dynamisk billeddannelse af kimære antigenreceptor-T-celler med [18F]tetrafluorborat positronemissionstomografi/computertomografi

Article DOI: 10.3791/62334-v • 09:34 min • February 17th, 2022
February 17th, 2022 •
1,2, 1,2, 3, 1,2,4,5, 1,2, 3, 3, 3, 3, 1,2, 1,2,5,6
1T Cell Engineering, Mayo Clinic, 2Division of Hematology, Mayo Clinic, 3Department of Radiology, Mayo Clinic, 4Regenerative Sciences PhD, Mayo Clinic, 5Department of Molecular Medicine, Mayo Clinic, 6Department of Immunology, Mayo Clinic

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Denne protokol beskriver metoden til ikke-invasiv sporing af T-celler, der er genetisk manipuleret til at udtrykke kimære antigenreceptorer in vivo med en klinisk tilgængelig platform.

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Kræftforskning udgave 180 CAR T-celle NIS-reporter [18F]TFB-PET ikke-invasiv billeddannelse
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