Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Medicine / Advanced Cardiac Rhythm Management by Applying…
JoVE Journal
Medicine

A subscription to JoVE is required to view this content.

JoVE Journal Medicine
Advanced Cardiac Rhythm Management by Applying Optogenetic Multi-Site Photostimulation in Murine Hearts
An in vivo Assay to Test Blood Vessel Permeability
Journal (Medicine)
An in vivo Assay to Test Blood Vessel Permeability
Development of an Audio-based Virtual Gaming Environment to Assist with Navigation Skills in the Blind
Journal (Medicine)
Development of an Audio-based Virtual Gaming Environment to Assist with Navigation Skills in the Blind
 

Advanced Cardiac Rhythm Management by Applying Optogenetic Multi-Site Photostimulation in Murine Hearts

Article DOI: 10.3791/62335-v • 08:43 min • August 26th, 2021
August 26th, 2021 •
*1,2, *1, 8,9, 1,3,4,6, 8,9, 1,5,6,7
1Research Group Biomedical Physics, Max Planck Institute for Dynamics and Self-Organization, 2Research Electronics Department, Max Planck Institute for Dynamics and Self-Organization, 3Department of Pharmacology and Toxicology, University Medical Center Goettingen, 4Institute for Nonlinear Dynamics, Georg-August-University Goettingen, 5Department of Cardiology and Pneumology, University Medical Center Goettingen, 6German Center for Cardiovascular Research, DZHK e.V., partner site Goettingen, 7Laboratory Animal Science Unit, German Primate Center Leibniz Institute for Primate Research, 8Department of Microsystems Engineering (IMTEK), University of Freiburg, 9Cluster of Excellence BrainLinks-BrainTools, University of Freiburg
* These authors contributed equally

Chapters

Summary
Automatic Translation

This work reports a method for controlling the cardiac rhythm of intact murine hearts of transgenic channelrhodopsin-2 (ChR2) mice using local photostimulation with a micro-LED array and simultaneous optical mapping of epicardial membrane potential.

Tags

Cardiac Rhythm Management Optogenetic Multi-site Photostimulation Murine Hearts Cardiac Fibrillation Defibrillation Optogenetics Cardiac Tissue Stimulation Anti-arrhythmic Therapy Cardiac Arrhythmia Large Animal Models De-mineralized Water Carbogen Sodium Hydroxide Hydrochloric Acid Perfusion System Water Bath Heating Element Thyroid Solutions
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter