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JoVE Journal Bioengineering
Geração de um modelo simplificado de pele em um chip tridimensional em uma plataforma microfluida micromaquinda
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Geração de um modelo simplificado de pele em um chip tridimensional em uma plataforma microfluida micromaquinda

Article DOI: 10.3791/62353-v • 06:30 min • May 17th, 2021
May 17th, 2021 •
1, 1, 2, 3, 1,4
1Department of Bioengineering and Aerospace Engineering, Universidad Carlos III de Madrid (UC3M), 2Group of Optics, Photonics and Biophotonics (GOFB). Center for Biomedical Technology, Universidad Politécnica de Madrid, 3Division of Epithelial Biomedicine, CIEMAT, 4Instituto de Investigación Sanitaria Gregorio Marañón

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Aqui, apresentamos um protocolo para gerar um modelo de pele simplificado e indiferenciado tridimensional usando uma plataforma microfluida micromaquinda. Uma abordagem de fluxo paralelo permite a deposição in situ de um compartimento dérmico para a semeadura de células epiteliais em cima, todas controladas por bombas de seringa.

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Bioengenharia Edição 171
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