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Behavior

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JoVE Journal Behavior
A Within-Subject Experimental Design using an Object Location Task in Rats
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A Within-Subject Experimental Design using an Object Location Task in Rats

Article DOI: 10.3791/62458-v • 09:28 min • May 6th, 2021
May 6th, 2021 •
*1,2, *1,3, 1,4, 1,5
1Danish Research Institute of Translational Neuroscience (DANDRITE), Department of Biomedicine, Aarhus University, 2Universitätsklinikum Würzburg, Institut für Klinische Neurobiologie, 3Translational Neuropsychiatry Unit, Department of Clinical Medicine, Aarhus University, 4Faculty of Science, Radboud University, 5Center for Proteins in Memory - PROMEMO, Danish National Research Foundation, Department of Biomedicine, Aarhus University
* These authors contributed equally

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Summary
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This protocol provides detailed steps for an object location task with four repetitions using the same cohort of rats. Weak and strong encoding can produce short- and long-term memories. The flexibility of the protocol with repetition can be beneficial for studies involving surgical operations by saving time and labor.

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Within-Subject Experimental Design Object Location Task Spatial Memory Explorative Behavior Rodents Statistical Power Surgical Procedures Square Arena Opaque Plastic Non-porous Automated Software Floor Color Contrast Context Creation Insertable Walls 3D Spatial Cues Geometric Shapes Colors Non-porous Objects Distinct Textures Bedding Material Random Object Placement Home Cages
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