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JoVE Journal Neuroscience
Billeddannelse og kvantificering af intakte neuronale dendritter via CLARITY Tissue Clearing
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Billeddannelse og kvantificering af intakte neuronale dendritter via CLARITY Tissue Clearing

Article DOI: 10.3791/62532-v • 07:45 min • April 20th, 2021
April 20th, 2021 •
1, 1,2, 1,2, 2, 1,3
1Department of Genetics and Genomics, Baylor College of Medicine, 2Medical Scientist Training Program, Baylor College of Medicine, 3Department of Neuroscience, Baylor College of Medicine

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Neuronal dendritisk morfologi ligger ofte til grund for funktion. Faktisk manifesterer mange sygdomsprocesser, der påvirker udviklingen af neuroner, sig med en morfologisk fænotype. Denne protokol beskriver en enkel og kraftfuld metode til analyse af intakte dendritiske arbors og deres tilknyttede pigge.

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Neurovidenskab udgave 170
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